Global equities tumbled, the dollar strengthened and volatility surged across asset classes as a fast-spreading new coronavirus strain in Britain threatened to torpedo markets’ optimism over a vaccine-fuelled rebound in economic growth.

Wall Street was tipped to open sharply lower.

The strain, said to be up to 70% more transmissible than the original, has put some 16 million Britons under tougher lockdowns and prompted several countries to shut their borders to the UK, effectively overshadowing positive U.S. news on a much-needed stimulus bill.

The shutdown of international travel and the flow of freight in and out of Britain threatens chaos for British households and businesses.

Coinciding with the lack of a post-Brexit trade deal ahead of the Dec. 31 deadline, it sent the pound 2.5% lower below $1.32 at one point, though the currency clawed back some of the losses to trade around $1.3285 by 1250 GMT.

Markets broadly edged off earlier lows though most stayed firmly in the red. UK equities were down just over 2%, while UK banks Lloyds and Barclays lost more than 6% at one stage before recovering slightly.

European equities fell around 2.5%. Travel and leisure stocks lost 3.5%.

“Our base case, based on what we know, is that we will stay under strict lockdowns for weeks into the New Year,” said Emiel van den Heiligenberg, head of asset allocation at Legal & General Investment Management.

He said the strain had already likely entered Europe, meaning “countries that are not in lockdown will have no choice but to do that quickly and that’s what markets are reacting to.”

The selloffs triggered across-the-board increases in volatility, a measure of price swings on an asset class, taking Wall Street’s “fear gauge” the VIX to the highest since early November.

Currency volatility jumped too, with overnight sterling volatility approaching nine-month highs

Futures for the S&P 500 fell 1.8%, recouping some earlier falls, while Nasdaq futures were down 1.2% NQc1.

While safe-haven assets such as German and U.S. government bonds rallied, gold, which usually rises during times of turmoil, fell as much as 1.3% before clawing back some of that loss.

Its weakness on a day of big equity selloffs will rekindle memories of the market slump of March when investors sold assets en masse in a rush for the dollar.

On the positive side, U.S. congressional leaders have finally agreed a roughly $900 billion COVID-19 relief bill.

LGIM’s van den Heiligenberg predicted also that vaccine rollouts would limit market downside.

“A correction is justified but a very strong selloff would surprise us…because of the vaccine, by next March-April, we should be able to think about normalisation again,” he added.